In general, methanol carbs are set to run much richer than gasoline for the same size engine. As you don't know the 'proper' setting for your engine yet, I'd shut the main jet fully off then open it 1/4 of a turn and try and start it. As it failed to start I'd open it up by no more than 1/8 of a turn at a time and keep trying. You'll hear it start to fire as it gets closer to the proper setting. Brian seems to have luck with these things running straight out of the box for him but I wouldn't count on having the same luck. For me, getting a new engine running is 95% fiddling with the carb settings until I get it right. Ignition just needs to be reasonably close and cam timing can be off quite a lot and it will still run. But carbs have to be adjusted properly.